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Search Results to Michael Taylor

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One or more keywords matched the following items that are connected to Taylor, Michael

Item TypeName
Concept Gene Expression Regulation, Enzymologic
Concept Down-Regulation
Concept Allosteric Regulation
Concept Gene Expression Regulation, Neoplastic
Concept Up-Regulation
Concept Gene Expression Regulation, Developmental
Concept Gene Expression Regulation
Academic Article Identification of differentially expressed and developmentally regulated genes in medulloblastoma using suppression subtraction hybridization.
Academic Article Expression of MAGE and GAGE genes in medulloblastoma and modulation of resistance to chemotherapy. Laboratory investigation.
Academic Article MicroRNA-199b-5p impairs cancer stem cells through negative regulation of HES1 in medulloblastoma.
Academic Article The miR-17/92 polycistron is up-regulated in sonic hedgehog-driven medulloblastomas and induced by N-myc in sonic hedgehog-treated cerebellar neural precursors.
Academic Article The genetic and epigenetic basis of ependymoma.
Academic Article Tuberous sclerosis complex suppression in cerebellar development and medulloblastoma: separate regulation of mammalian target of rapamycin activity and p27 Kip1 localization.
Academic Article Normal and oncogenic roles for microRNAs in the developing brain.
Academic Article YAP1 is amplified and up-regulated in hedgehog-associated medulloblastomas and mediates Sonic hedgehog-driven neural precursor proliferation.
Academic Article OTX2 is critical for the maintenance and progression of Shh-independent medulloblastomas.
Academic Article Genetic and epigenetic inactivation of Kruppel-like factor 4 in medulloblastoma.
Academic Article HDAC5 and HDAC9 in medulloblastoma: novel markers for risk stratification and role in tumor cell growth.
Academic Article Pleiotropic role for MYCN in medulloblastoma.
Academic Article Cross-species genomics matches driver mutations and cell compartments to model ependymoma.
Academic Article Role of LIM and SH3 protein 1 (LASP1) in the metastatic dissemination of medulloblastoma.
Academic Article PCDH10 is a candidate tumour suppressor gene in medulloblastoma.
Academic Article MicroRNA-182 promotes leptomeningeal spread of non-sonic hedgehog-medulloblastoma.
Academic Article Monoallelic expression determines oncogenic progression and outcome in benign and malignant brain tumors.
Academic Article An animal model of MYC-driven medulloblastoma.
Academic Article Molecular subgroups of medulloblastoma: an international meta-analysis of transcriptome, genetic aberrations, and clinical data of WNT, SHH, Group 3, and Group 4 medulloblastomas.
Academic Article Voltage-gated potassium channel EAG2 controls mitotic entry and tumor growth in medulloblastoma via regulating cell volume dynamics.
Academic Article The RNA-binding protein Musashi1 affects medulloblastoma growth via a network of cancer-related genes and is an indicator of poor prognosis.
Academic Article Bmi1 overexpression in the cerebellar granule cell lineage of mice affects cell proliferation and survival without initiating medulloblastoma formation.
Academic Article Molecular subgroups of atypical teratoid rhabdoid tumours in children: an integrated genomic and clinicopathological analysis.
Academic Article Emerging insights into the ependymoma epigenome.
Academic Article Methylation of the TERT promoter and risk stratification of childhood brain tumours: an integrative genomic and molecular study.
Academic Article Somatostatin receptor subtype 2 (sst2) is a potential prognostic marker and a therapeutic target in medulloblastoma.
Academic Article Neogenin1 is a Sonic Hedgehog target in medulloblastoma and is necessary for cell cycle progression.
Academic Article MyoD is a tumor suppressor gene in medulloblastoma.
Academic Article Fusion of TTYH1 with the C19MC microRNA cluster drives expression of a brain-specific DNMT3B isoform in the embryonal brain tumor ETMR.
Academic Article Polycomb group gene BMI1 controls invasion of medulloblastoma cells and inhibits BMP-regulated cell adhesion.
Academic Article Cytogenetic prognostication within medulloblastoma subgroups.
Academic Article Integrated genomic analysis identifies the mitotic checkpoint kinase WEE1 as a novel therapeutic target in medulloblastoma.
Academic Article Decoding the regulatory landscape of medulloblastoma using DNA methylation sequencing.
Academic Article CNS-PNETs with C19MC amplification and/or LIN28 expression comprise a distinct histogenetic diagnostic and therapeutic entity.
Academic Article Quiescent sox2(+) cells drive hierarchical growth and relapse in sonic hedgehog subgroup medulloblastoma.
Academic Article ATM regulates 3-methylpurine-DNA glycosylase and promotes therapeutic resistance to alkylating agents.
Academic Article Gene-expression profiling elucidates molecular signaling networks that can be therapeutically targeted in vestibular schwannoma.
Academic Article The Shh receptor Boc promotes progression of early medulloblastoma to advanced tumors.
Academic Article Molecular characterization of choroid plexus tumors reveals novel clinically relevant subgroups.
Academic Article An epigenetic therapy for diffuse intrinsic pontine gliomas.
Academic Article SnapShot: Medulloblastoma.
Academic Article A microRNA-1280/JAG2 network comprises a novel biological target in high-risk medulloblastoma.
Academic Article Response.
Academic Article Mechanism of action and therapeutic efficacy of Aurora kinase B inhibition in MYC overexpressing medulloblastoma.
Academic Article Spinal Myxopapillary Ependymomas Demonstrate a Warburg Phenotype.
Academic Article MLL5 Orchestrates a Cancer Self-Renewal State by Repressing the Histone Variant H3.3 and Globally Reorganizing Chromatin.
Academic Article Medulloblastoma-associated DDX3 variant selectively alters the translational response to stress.
Academic Article Norrin/Frizzled4 signalling in the preneoplastic niche blocks medulloblastoma initiation.
Academic Article Spatial heterogeneity in medulloblastoma.
Academic Article 5-Hydroxymethylcytosine preferentially targets genes upregulated in isocitrate dehydrogenase 1 mutant high-grade glioma.
Academic Article Metastatic group 3 medulloblastoma is driven by PRUNE1 targeting NME1-TGF-ß-OTX2-SNAIL via PTEN inhibition.
Academic Article Mutations in SUFU predispose to medulloblastoma.
Academic Article Therapeutic targeting of ependymoma as informed by oncogenic enhancer profiling.
Academic Article DNA methylation profiling of medulloblastoma allows robust subclassification and improved outcome prediction using formalin-fixed biopsies.
Academic Article miR miR on the wall, who's the most malignant medulloblastoma miR of them all?
Academic Article Molecular heterogeneity and CXorf67 alterations in posterior fossa group A (PFA) ependymomas.
Academic Article Developmental phosphoproteomics identifies the kinase CK2 as a driver of Hedgehog signaling and a therapeutic target in medulloblastoma.
Academic Article Aberrant ERBB4-SRC Signaling as a Hallmark of Group 4 Medulloblastoma Revealed by Integrative Phosphoproteomic Profiling.
Academic Article Bioinformatic Strategies for the Genomic and Epigenomic Characterization of Brain Tumors.
Academic Article Notch1 regulates the initiation of metastasis and self-renewal of Group 3 medulloblastoma.
Academic Article BMI1 is a therapeutic target in recurrent medulloblastoma.
Academic Article DNA hypermethylation within TERT promoter upregulates TERT expression in cancer.
Academic Article Childhood cerebellar tumours mirror conserved fetal transcriptional programs.
Academic Article ID1 Is Critical for Tumorigenesis and Regulates Chemoresistance in Glioblastoma.
Academic Article A C19MC-LIN28A-MYCN Oncogenic Circuit Driven by Hijacked Super-enhancers Is a Distinct Therapeutic Vulnerability in ETMRs: A Lethal Brain Tumor.
Academic Article Modulating native GABAA receptors in medulloblastoma with positive allosteric benzodiazepine-derivatives induces cell death.
Academic Article Single-Cell Transcriptomics in Medulloblastoma Reveals Tumor-Initiating Progenitors and Oncogenic Cascades during Tumorigenesis and Relapse.
Academic Article Alterations in ALK/ROS1/NTRK/MET drive a group of infantile hemispheric gliomas.
Academic Article Stalled developmental programs at the root of pediatric brain tumors.
Academic Article The AHR pathway represses TGFß-SMAD3 signalling and has a potent tumour suppressive role in SHH medulloblastoma.
Academic Article p53 Function Is Compromised by Inhibitor 2 of Phosphatase 2A in Sonic Hedgehog Medulloblastoma.
Academic Article Integrated Molecular and Clinical Analysis of 1,000 Pediatric Low-Grade Gliomas.
Academic Article Metabolic Regulation of the Epigenome Drives Lethal Infantile Ependymoma.
Academic Article Upregulation of the chromatin remodeler HELLS is mediated by YAP1 in Sonic Hedgehog Medulloblastoma.

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